Development and evaluation of topical formulations that contain hydroethanolic extract from Schinus terebinthifolia against HSV-1 infection

• Published in: Brazilian Journal of Pharmaceutical Sciences Vol. 58
• Main Authors: Nocchi, Samara Requena, Ferreira, Lilian dos Anjos Oliveira, Castro-Hoshino, Lidiane Vizioli de, Truiti, Maria da Conceição Torrado, Natali, Maria Raquel Marçal, Mello, João Carlos Palazzo de, Baesso, Mauro Luciano, Dias Filho, Benedito Prado, Nakamura, Celso Vataru, Ueda-Nakamura, Tânia
• Format: Journal Article
• Language: English
• Published: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2022
• Subjects: PHARMACOLOGY & PHARMACY; Photoacoustic; Skin irritation; HSV-1; Topical formulations; In vivo efficacy; Schinus terebinthifolia

Abstract The therapeutic drugs to treat Herpes simplex virus (HSV) infections have toxic side effects and there has been an emergence of drug-resistant strains. Therefore, the search for new treatments for HSV infections is mounting. In the present study, semi-solid formulations containing a crude h...