Characterization of osteogenic cells grown over modified graphene-oxide-biostable polymers

• Published in: Biomedical materials (Bristol) Vol. 14; no. 6; p. 065004
• Main Authors: Mirza, Eraj Humayun, Khan, Aftab Ahmed, Al-Khureif, Abdulaziz Abdullah, Saadaldin, Selma Adnan, Mohamed, Badreldin Abdelrhaman, Fareedi, Fatima, Khan, Muhammad Muzammil, Alfayez, Musaad, Al-Fotawi, Randa, Vallittu, Pekka K, Mahmood, Amer
• Format: Journal Article
• Language: English
• Published: England IOP Publishing 09.09.2019
• Subjects: Bone and Bones - metabolism; Bone Cements - chemistry; bone tissue; Calcium Phosphates; Cell Differentiation - drug effects; Cell Proliferation - drug effects; Cell Survival; Colorimetry; gene expression; graphene oxide; Graphite - chemistry; Humans; Mesenchymal Stem Cells - cytology; osteoblasts; Osteoblasts - cytology; Osteogenesis - drug effects; Phenotype; poly(methyl methacrylate) (PMMA); Polymers - chemistry; Polymethacrylic Acids - chemistry; Spectrum Analysis, Raman; Surface Properties; Tissue Engineering

Graphene is an excellent filler for the development of reinforced composites. This study evaluated bone cement composites of graphene oxide (GO) and poly(methyl methacrylate) (PMMA) based on the proliferation of human bone marrow mesenchymal stem cells (hBMSCs), and the anabolic and catabolic effect...