The global dissemination of bacterial infections necessitates the study of reverse genomic epidemiology

• Published in: Briefings in bioinformatics Vol. 21; no. 2; pp. 741 - 750
• Main Authors: Ruan, Zhi, Yu, Yunsong, Feng, Ye
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 23.03.2020; Oxford Publishing Limited (England)
• Subjects: Bacteria; Bacterial diseases; Bacterial infections; Epidemiology; Gene sequencing; Genomes; Genomics; Genotyping; Infectious diseases; Outbreaks; Pathogens; Public health; Standardization; Tracing; Whole genome sequencing; outbreak tracking; global surveillance; bacterial infectious diseases; reverse genomic epidemiology; Whole genome sequencing

Abstract Whole genome sequencing (WGS) has revolutionized the genotyping of bacterial pathogens and is expected to become the new gold standard for tracing the transmissions of bacterial infectious diseases for public health purposes. Traditional genomic epidemiology often uses WGS as a verification...