The environmental stress sensitivities of pathogenic Candida species, including Candida auris, and implications for their spread in the hospital setting

• Published in: Medical mycology (Oxford) Vol. 58; no. 6; p. 744
• Main Authors: Heaney, Helen, Laing, Juliette, Paterson, Linda, Walker, Alan W, Gow, Neil A R, Johnson, Elizabeth M, MacCallum, Donna M, Brown, Alistair J P
• Format: Journal Article
• Language: English
• Published: England 01.08.2020
• Subjects: Antifungal Agents - pharmacology; Bedding and Linens - microbiology; Candida - classification; Candida - drug effects; Candida - pathogenicity; Candidiasis - microbiology; Candidiasis - transmission; Drug Resistance, Fungal; Environment; Equipment and Supplies, Hospital - microbiology; Hospitals; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Nitrosative Stress; Oxidative Stress; Stress, Physiological; Thermotolerance; Candida auris; stress resistance; Candida pathogens; decontamination; hospital laundry

Candida auris is an emerging pathogenic yeast of significant clinical concern because of its frequent intrinsic resistance to fluconazole and often other antifungal drugs and the high mortality rates associated with systemic infections. Furthermore, C. auris has a propensity for persistence and tran...