β‑catenin regulates effects of miR‑24 on the viability and autophagy of glioma cells

• Published in: Experimental and therapeutic medicine Vol. 18; no. 2; pp. 1285 - 1290
• Main Authors: Chen, Hanchun, Lu, Qiong, Chen, Chao, Di, Yunhai, Li, Ya'nan, Min, Weijie, Yu, Zhengquan, Dai, Dongwei
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications UK Ltd 01.08.2019; D.A. Spandidos
• Subjects: Antibiotics; Apoptosis; Autophagy; Binding sites; Biotechnology; Brain cancer; Cell adhesion & migration; Cell cycle; Cell growth; Colorectal cancer; Glioma; Kinases; Laboratory animals; Liver cancer; Lung cancer; Medical prognosis; Mutation; Prostate cancer; Protein expression; Proteins; Skin cancer; Tumors; Beijing China; United States > US; China; microRNA-24; β-catenin; autophagy; cell viability; glioma C6 cells

Mutations of the β-catenin gene are common in various cancer types. MicroRNA (miR)-24 suppresses gene expression during the cell cycle. However, the effects of miR-24 on the cell viability and autophagy of glioma cells, and how these biological processes are regulated by β-catenin are largely unclea...