CXCL8 derived from mesenchymal stromal cells supports survival and proliferation of acute myeloid leukemia cells through the PI3K/AKT pathway - Cheng, Jingying; Li, Ying; Liu, Shiqi; Jiang, Yajing; Ma, Jiao; Wan, Li; Li, Qinghua; Pang, Tianxiang (The FASEB journal, 2019)
Keywords: Adolescent; Adult; Aged; Apoptosis - drug effects; Blotting, Western; Cell Line, Tumor; Cell Proliferation - genetics; Cell Proliferation - physiology; Cell Survival - drug effects; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescent Antibody Technique; HL-60 Cells; Humans; Interleukin-8 - metabolism; Interleukin-8 - pharmacology; Leukemia, Myeloid, Acute - metabolism; Male; Mesenchymal Stem Cells - metabolism; Middle Aged; Phosphatidylinositol 3-Kinases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Real-Time Polymerase Chain Reaction; Signal Transduction - drug effects; Young Adult; cancer; cytokines; crosstalk; bone marrow microenvironment