The effect of duration of nasal obstruction on mean platelet volume in patients with marked nasal septal deviation

• Published in: European archives of oto-rhino-laryngology Vol. 273; no. 2; pp. 401 - 405
• Main Authors: Unlu, Ilhan, Kesici, Gulin Gokcen, Oneç, Birgul, Yaman, Huseyin, Guclu, Ender
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.02.2016
• Subjects: Adolescent; Adult; Aged; Female; Follow-Up Studies; Head and Neck Surgery; Humans; Male; Mean Platelet Volume - methods; Medicine; Medicine & Public Health; Middle Aged; Nasal Obstruction - blood; Nasal Obstruction - etiology; Nasal Obstruction - surgery; Nasal Septum - pathology; Nasal Septum - surgery; Neurosurgery; Nose Deformities, Acquired - blood; Nose Deformities, Acquired - complications; Nose Deformities, Acquired - surgery; Otorhinolaryngology; Platelet Count; Retrospective Studies; Rhinology; Time Factors; Young Adult; Mean platelet volume; Hypoxia; Nasal obstruction; Septoplasty
• ISSN: 0937-4477; 1434-4726
• DOI: 10.1007/s00405-015-3580-2

Nasal obstruction is a common cause of marked nasal septal deviation. It is related strongly with hypoxia. Hypoxic conditions increase mean platelet volume levels. This study aimed to investigate the effect of age on mean platelet volume in patients with marked nasal septal deviation. We made a retrospective study of patients with marked nasal septal deviation between January 2012 and May 2014. The patients were divided into four groups according to duration of nasal obstruction (less than 10, 10–20, 20–30 and more than 30 years). The groups were compared with each other in terms of mean platelet volume, platelet distribution width, platelet count in preoperative hemogram. This study was performed on 356 male and 139 female patients. Mean age was 33.9 ± 12.3 years. It was determined that the platelet count, mean platelet volume did not constitute statistically significant difference between groups ( p  > 0.05). Nevertheless, it was determined that as the duration of nasal obstruction elongated the mean platelet volume value increased and platelet count values decreased. Mean values of platelet distribution width constituted statistically significant difference between all groups ( p  = 0.026). Patients with marked nasal septum deviation should be subjected to surgery as soon as possible because of the increase in mean platelet volume and platelet distribution width values which are related to increase in the risk of cardiopulmonary complications of nasal obstruction.