Activation of bystander CD8 + T cells in a pediatric patient with acute hepatitis E

• Published in: Immunological medicine pp. 1 - 7
• Main Authors: Morita, Atsushi, Imagawa, Kazuo, Iwasaki, Tomoya, Yaita, Katsuyuki, Sakai, Aiko, Takada, Hidetoshi
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis Group 16.07.2024
• Subjects: Complementary determining region 3; cytokine; human leukocyte antigen; T cell receptor; Th1; cytokine; Complementary determining region 3; T cell receptor; Th1; human leukocyte antigen

Most children with acute hepatitis A virus (HAV) or hepatitis E virus (HEV) infection are asymptomatic. Bystander CD8 T-cell activation has garnered attention owing to its possible pathophysiological role in adult hepatitis. However, no reports have studied it in pediatric hepatitis. Herein, we desc...