Intraocular Concentration of Stem Cell Factor/c-KIT and Galectin-1 in Retinal Diseases

• Published in: Investigative ophthalmology & visual science Vol. 65; no. 11; p. 11
• Main Authors: Choi, Yong Je, Kim, Hyeong Min, Park, Kyu Hyung, Park, Sang Gyu, Woo, Se Joon
• Format: Journal Article
• Language: English
• Published: United States The Association for Research in Vision and Ophthalmology 06.09.2024
• Subjects: Aged; Aged, 80 and over; Angiogenesis Inhibitors - therapeutic use; Aqueous Humor - metabolism; Diabetic Retinopathy - drug therapy; Diabetic Retinopathy - metabolism; Female; Galectin 1 - metabolism; Humans; Intravitreal Injections; Macular Degeneration - drug therapy; Macular Degeneration - metabolism; Macular Edema - drug therapy; Macular Edema - metabolism; Male; Middle Aged; Proto-Oncogene Proteins c-kit - metabolism; Retina; Retinal Diseases - drug therapy; Retinal Diseases - metabolism; Retinal Vein Occlusion - drug therapy; Retinal Vein Occlusion - metabolism; Stem Cell Factor - metabolism; Vascular Endothelial Growth Factor A - metabolism

To investigate the intraocular concentration profiles of stem cell factor (SCF)/c-KIT, galectin-1 (GAL-1), and vascular endothelial growth factor (VEGF)-A with regard to retinal disease and treatment response. The study group included 13 patients with dry age-related macular degeneration (AMD), 196...