Tetraphenylethylene-doped covalent organic frameworks as a highly efficient aggregation-induced electrochemiluminescence emitter for ultrasensitive miRNA-21 analysis

• Published in: Advanced Sensor and Energy Materials Vol. 2; no. 2; p. 100059
• Main Authors: Shu, Wen-Yi, Su, Ruiqi, Yao, Linli, Xiao, Yao, Chen, Miao-Miao, Wen, Wei, Wang, Shengfu, Xiong, Chengyi, Zhang, Xiuhua
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2023; Elsevier
• Subjects: Aggregation-induced electrochemiluminescence; Biosensor; Covalent organic frameworks; MicroRNA-21; Resonance energy transfer; Covalent organic frameworks; Resonance energy transfer; MicroRNA-21; Aggregation-induced electrochemiluminescence; Biosensor

MicroRNAs (miRNAs) as a well-known kind of cancer marker are closely associated with the formation and metastasis of tumors. Here, a novel tetraphenylethylene (TPE)-doped covalent organic frameworks (TPE-COFs) with strong aggregation-induced electrochemiluminescence (AIECL) response was synthesized...