Effect of Paired Associative Stimulation on Motor Cortex Excitability in Rats

• Published in: Current medical science Vol. 38; no. 5; pp. 903 - 909
• Main Authors: Zhang, Xiang-yu, Sui, Yan-fang, Guo, Tie-cheng, Wang, Sai-hua, Hu, Yan, Lu, Yin-shan
• Format: Journal Article
• Language: English
• Published: Wuhan Huazhong University of Science and Technology 01.10.2018
• Subjects: Animals; Electric Stimulation; Evoked Potentials, Motor - physiology; Evoked Potentials, Somatosensory - physiology; Humans; Long-Term Potentiation - physiology; Male; Medicine; Medicine & Public Health; Motor Cortex - physiology; Muscle, Skeletal - physiology; Neuronal Plasticity - physiology; Rats; Rats, Sprague-Dawley; Reaction Time - physiology; Transcranial Magnetic Stimulation; electrical stimulation; resting motor thresholds; motor evoked potentials; peripheral nerves; paired associative stimulation; transcranial magnetic stimulation; somatosensory evoked potentials

Paired associative stimulation (PAS), combining transcranial magnetic stimulation (TMS) with electrical peripheral nerve stimulation (PNS) in pairs with an optimal interstimulus interval (ISI) in between, has been shown to influence the excitability of the motor cortex (MC) in humans. However, the u...