Controllable synthesis of benzoxazinones and 2-hydroxy-3-indolinones by visible-light-promoted 5-endo-dig N-radical cyclization cascade

• Published in: Cell reports physical science Vol. 2; no. 10; p. 100577
• Main Authors: Tan, Tong-De, Zhai, Tong-Yi, Liu, Bin-Yang, Li, Long, Qian, Peng-Cheng, Sun, Qing, Zhou, Jin-Mei, Ye, Long-Wu
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 20.10.2021
• Subjects: cyclizations; heterocycles; photocatalysis; radicals; tandem reaction; cyclizations; tandem reaction; radicals; photocatalysis; heterocycles

In recent years, significant advances have been made on photoredox-catalyzed N-radical addition to C-C unsaturated bond via N-H bond cleavage. However, these N-centered radical additions have so far been mostly limited to the alkenes, and to our knowledge, N-radical 5-endo-dig cyclizations of alkyne...