Enhancing subcellular protein localization mapping analysis using Sc2promap utilizing attention mechanisms

• Published in: Biochimica et biophysica acta. General subjects Vol. 1868; no. 6; p. 130601
• Main Authors: Han, Kaitai, Liu, Xi, Sun, Guocheng, Wang, Zijun, Shi, Chaojing, Liu, Wu, Huang, Mengyuan, Liu, Shitou, Guo, Qianjin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.06.2024
• Subjects: Algorithms; automation; bioinformatics; Cluster Analysis; Clustering; Computational Biology - methods; Endogenous labeled proteins; fluorescence; head; Humans; Image Processing, Computer-Assisted - methods; Large-scale protein image analysis; prediction; Protein Transport; Proteins - metabolism; Spatial and channel attention; Subcellular protein localization; Vector quantization; Subcellular protein localization; Large-scale protein image analysis; Endogenous labeled proteins; Spatial and channel attention; Vector quantization; Clustering

Aberrant protein localization is a prominent feature in many human diseases and can have detrimental effects on the function of specific tissues and organs. High-throughput technologies, which continue to advance with iterations of automated equipment and the development of bioinformatics, enable th...