Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus - Gant, J. C.; Chen, K.-C.; Kadish, I.; Blalock, E. M.; Thibault, O.; Porter, N. M.; Landfield, P. W. (The Journal of neuroscience, 2015)
Keywords: Aging - physiology; Animals; Calcium - metabolism; Cognition - physiology; Cognition Disorders - etiology; Cognition Disorders - metabolism; Hippocampus - metabolism; Immunohistochemistry; Male; Neurons - metabolism; Patch-Clamp Techniques; Rats; Rats, Inbred F344; Rats, Transgenic; Real-Time Polymerase Chain Reaction; Tacrolimus Binding Proteins - metabolism; Transgenes; FKBP; calcium; memory; aging; ryanodine receptor; Alzheimer's disease