Formulation analyses of high-volume prescription drugs

• Published in: Powder diffraction Vol. 34; no. 2; pp. 130 - 142
• Main Authors: Fawcett, T.G., Gates-Rector, S., Gindhart, A.M., Rost, M., Kabekkodu, S.N., Blanton, J. R., Blanton, T. N.
• Format: Journal Article
• Language: English
• Published: New York, USA Cambridge University Press 01.06.2019
• Subjects: Allergies; Analgesics; Antibiotics; Anticoagulants; Blood pressure; Cellulose; Cholesterol; Coherent scattering; Collection; Constipation; Datasets; Dementia; Diabetes; Diffraction patterns; Drugs; Excipients; Formulations; Gastroesophageal reflux; Incoherent scattering; Ingredients; Laboratories; Lactose; Low concentrations; Methods; Narcotics; Pain; Pattern matching; Pharmaceuticals; Phase composition; Prescription drugs; Software; Tablets; Technical Article; United States > US; pharmaceutical; amorphous; formulations; powder diffraction

A collection of 65 formulated tablets and capsules were analyzed for phase composition by full pattern matching powder diffraction methods. The collection contained 32 of the top 200 prescription drugs sold in 2016 as well as many high-volume prescriptions and over the counter drugs from prior years...