Changes in serum interleukin-2, -6, and -8 levels before and during treatment with risperidone and haloperidol: relationship to outcome in schizophrenia

• Published in: The journal of clinical psychiatry Vol. 65; no. 7; p. 940
• Main Authors: Zhang, Xiang Yang, Zhou, Dong Feng, Cao, Lian Yuan, Zhang, Pei Yan, Wu, Gui Ying, Shen, Yu Cun
• Format: Journal Article
• Language: English
• Published: United States 01.07.2004
• Subjects: Adult; Antipsychotic Agents - pharmacology; Antipsychotic Agents - therapeutic use; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Haloperidol - pharmacology; Haloperidol - therapeutic use; Hospitalization; Humans; Immunity, Cellular - drug effects; Interleukin-2 - blood; Interleukin-2 - immunology; Interleukin-6 - blood; Interleukin-6 - immunology; Interleukin-8 - blood; Interleukin-8 - immunology; Male; Radioimmunoassay; Risperidone - pharmacology; Risperidone - therapeutic use; Schizophrenia - blood; Schizophrenia - drug therapy; Schizophrenia - immunology; Treatment Outcome

Many studies have indicated that immune cytokines may be involved in the pathophysiology of schizophrenia. Recently, there have been reports that typical and atypical antipsychotic drugs may influence the levels of cytokines or cytokine receptors. The aim of this study was to compare the effect of t...