High-resolution melting curve analysis of polymorphisms within CD58, CD226, HLA-G genes and association with multiple sclerosis susceptibility in a subset of Iranian population: a case–control study

• Published in: Acta neurologica Belgica Vol. 120; no. 3; pp. 645 - 652
• Main Authors: Ghavimi, Reza, Alsahebfosoul, Fereshteh, Salehi, Rasoul, Kazemi, Mohammad, Etemadifar, Masoud, Zavaran Hosseini, Ahmad
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.06.2020
• Subjects: Adult; Antigens, Differentiation, T-Lymphocyte - genetics; Asian Continental Ancestry Group - genetics; Biomedical and Life Sciences; Biomedicine; Case-Control Studies; CD58 Antigens - genetics; Female; Genetic Predisposition to Disease - genetics; HLA-G Antigens - genetics; Humans; Iran; Male; Medicine/Public Health; Multiple Sclerosis, Relapsing-Remitting - genetics; Neurology; Neuroradiology; Neurosciences; Original Article; Polymorphism, Single Nucleotide; Iran; Multiple sclerosis; CD226; CD58; Single nucleotide polymorphisms; HLA-G

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with unknown etiology, which typically is manifested in early to middle adulthood. Recently, genome-wide association studies have identified susceptibility of immune-related genes to be involved in...