Transcriptomic analysis of HEK293A cells with a CRISPR/Cas9-mediated TDP1 knockout - Dyrkheeva, Nadezhda S.; Zakharenko, Alexandra L.; Malakhova, Anastasia A.; Okorokova, Larisa S.; Shtokalo, Dmitry N.; Medvedev, Sergey P.; Tupikin, Alexey A.; Kabilov, Marsel R.; Lavrik, Olga I. (Biochimica et biophysica acta. General subjects, 2024)
Keywords: cancer therapy; cell adhesion; cell lines; CRISPR-Cas Systems; cytokines; DNA; DNA repair; DNA Repair - genetics; family; Gene Expression Profiling; Gene Knockout Techniques - methods; gene targeting; genes; HEK293 Cells; HEK293A; homozygosity; Humans; mitochondria; neurodegenerative diseases; phospholipases; Phosphoric Diester Hydrolases - genetics; Phosphoric Diester Hydrolases - metabolism; spermatogenesis; TDP1 knockout; Topoisomerase 1; Transcriptome; Transcriptome - genetics; transcriptomics; Tyrosyl-DNA phosphodiesterase 1; Topoisomerase 1; Tyrosyl-DNA phosphodiesterase 1; HEK293A; TDP1 knockout; Transcriptome