Gastrodin attenuates lithium-pilocarpine-induced epilepsy by activating AMPK-mediated PPARα in a juvenile rat model

• Published in: Bioscience, biotechnology, and biochemistry Vol. 85; no. 4; pp. 798 - 804
• Main Authors: Yang, Yanfei, Li, Yabin, Han, Jinli, Wang, Yanfen
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 24.03.2021
• Subjects: AMPK; gastrodin; PPARα; pediatric epilepsy

ABSTRACT Gastrodin has shown the potential as an anticonvulsant. Epilepsy is a neurological disease with significant effects in children. In the current study, the therapeutic potential of gastrodin in handling pediatric epilepsy was explored by focusing on the AMPK/PPARα pathway. Three-week-old Spr...