Development and validation of a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method including 25 novel synthetic opioids in hair and subsequent analysis of a Swiss opioid consumer cohort

• Published in: Drug testing and analysis Vol. 16; no. 11; pp. 1384 - 1391
• Main Authors: Polke, Max, Concheiro, Marta, Cooper, Gail, Bogdal, Christian, Baumgartner, Markus R., Krämer, Thomas, Binz, Tina M.
• Format: Journal Article
• Language: English
• Published: England 01.11.2024
• Subjects: fentanyl; hair analysis; LC–MS/MS; NSOs; Switzerland; hair analysis; LC-MS/MS; NSOs; Switzerland; fentanyl

Major public health concern is raised by the evidence that common drugs like heroin are now frequently laced or replaced with highly potent novel synthetic opioids (NSOs). The objective of this study was to explore the prevalence and patterns of NSOs in a cohort of Swiss opioid users by hair analysi...