Aldehyde dehydrogenase 2 protects against abdominal aortic aneurysm formation by reducing reactive oxygen species, vascular inflammation, and apoptosis of vascular smooth muscle cells - Tsai, Shih-Hung; Hsu, Lung-An; Tsai, Hsiao-Ya; Yeh, Yung-Hsin; Lu, Cheng-Yo; Chen, Po-Chuan; Wang, Jen-Chun; Chiu, Yi-Lin; Lin, Chih-Yuan; Hsu, Yu-Juei (The FASEB journal, 2020)
Keywords: Aldehyde Dehydrogenase, Mitochondrial - physiology; Animals; Aortic Aneurysm, Abdominal - immunology; Aortic Aneurysm, Abdominal - metabolism; Aortic Aneurysm, Abdominal - pathology; Aortic Aneurysm, Abdominal - prevention & control; Apoptosis; Disease Models, Animal; Female; Inflammation - immunology; Inflammation - metabolism; Inflammation - pathology; Inflammation - prevention & control; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria - immunology; Mitochondria - metabolism; Mitochondria - pathology; Muscle, Smooth, Vascular - immunology; Muscle, Smooth, Vascular - metabolism; Muscle, Smooth, Vascular - pathology; Oxidative Stress; Protective Agents; Reactive Oxygen Species - metabolism; aldehyde dehydrogenase 2; 4-hydroxy-2-nonenal; angiotensin II; abdominal aortic aneurysm; reactive oxygen species