Exploring Circulating Tumor DNA (CtDNA) and Its Role in Early Detection of Cancer: A Systematic Review

• Published in: Curēus (Palo Alto, CA) Vol. 15; no. 9; p. e45784
• Main Authors: Bittla, Parikshit, Kaur, Simran, Sojitra, Vani, Zahra, Anam, Hutchinson, Jhenelle, Folawemi, Oluwa, Khan, Safeera
• Format: Journal Article
• Language: English
• Published: United States Springer Nature B.V 22.09.2023; Cureus
• Subjects: Biopsy; Breast cancer; Case reports; Cervical cancer; DNA methylation; Editorials; Esophagus; Mammography; Medical prognosis; Medical screening; Medical Subject Headings-MeSH; Meta-analysis; Mortality; Mutation; Observational studies; Oncology; Other; Preventive Medicine; Prostate cancer; Systematic review; Text messaging; Tumors; medical screening; prevention in primary care; early detection of cancer; circulating tumor dna (ctdna); liquid biopsy

There is a significant increase in the need for an efficient screening method that might identify cancer at an early stage and could improve patients' long-term survival due to the continued rise in cancer incidence and associated mortality. One such effort involved using circulating tumor DNA...