Carcinogenic and health risk assessment of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene in the petrochemical industry using the US Environmental Protection Agency method

Objectives. This study aimed to assess carcinogenic and health risks of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene (ABS) in the petrochemical industry. Methods. This cross-sectional study was conducted in a petrochemical plant producing ABS copolymers. Respiratory exposure to e...

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Published inInternational journal of occupational safety and ergonomics Vol. 28; no. 4; pp. i - ix
Main Authors Ahmadi-Moshiran, Vahid, Sajedian, Ali Asghar, Soltanzadeh, Ahmad, Seifi, Fatemeh, Koobasi, Rozhin, Nikbakht, Neda, Sadeghi-Yarandi, Mohsen
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LanguageEnglish
Published Taylor & Francis 02.10.2022
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Abstract Objectives. This study aimed to assess carcinogenic and health risks of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene (ABS) in the petrochemical industry. Methods. This cross-sectional study was conducted in a petrochemical plant producing ABS copolymers. Respiratory exposure to each of acrylonitrile, 1,3-butadiene and styrene was measured using methods No. 1604, No. 1024 and No. 1501 of the National Institute of Occupational Safety and Health (NIOSH), respectively. The US Environmental Protection Agency (USEPA) method was used to assess carcinogenic and health risks. Results. The average occupational exposure to ABS was 560.82 µg m -3 for 1,3-butadiene, 122.8 µg m -3 for acrylonitrile and 1.92 µg m -3 for styrene. The average lifetime cancer risk in the present study was 2.71 × 10 −3 for 1,3-butadiene, 2.1 × 10 −3 for acrylonitrile and 6.6 × 10 −3 for styrene. Also, the mean non-cancer risk (hazard quotient) among all participants for each of 1,3-butadiene, acrylonitrile and styrene was 4.04 ± 6.93, 10.82 ± 14.76 and 0.19 ± 0.11, respectively. Conclusion. The values of carcinogenic and health risks in the majority of the subjects were within the unacceptable risk levels due to exposure to ABS vapors. Hence, corrective actions are required to protect the workers from non-cancer and cancer risks.
AbstractList Objectives. This study aimed to assess carcinogenic and health risks of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene (ABS) in the petrochemical industry. Methods. This cross-sectional study was conducted in a petrochemical plant producing ABS copolymers. Respiratory exposure to each of acrylonitrile, 1,3-butadiene and styrene was measured using methods No. 1604, No. 1024 and No. 1501 of the National Institute of Occupational Safety and Health (NIOSH), respectively. The US Environmental Protection Agency (USEPA) method was used to assess carcinogenic and health risks. Results. The average occupational exposure to ABS was 560.82 µg m -3 for 1,3-butadiene, 122.8 µg m -3 for acrylonitrile and 1.92 µg m -3 for styrene. The average lifetime cancer risk in the present study was 2.71 × 10 −3 for 1,3-butadiene, 2.1 × 10 −3 for acrylonitrile and 6.6 × 10 −3 for styrene. Also, the mean non-cancer risk (hazard quotient) among all participants for each of 1,3-butadiene, acrylonitrile and styrene was 4.04 ± 6.93, 10.82 ± 14.76 and 0.19 ± 0.11, respectively. Conclusion. The values of carcinogenic and health risks in the majority of the subjects were within the unacceptable risk levels due to exposure to ABS vapors. Hence, corrective actions are required to protect the workers from non-cancer and cancer risks.
Objectives. This study aimed to assess carcinogenic and health risks of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene (ABS) in the petrochemical industry. Methods. This cross-sectional study was conducted in a petrochemical plant producing ABS copolymers. Respiratory exposure to each of acrylonitrile, 1,3-butadiene and styrene was measured using methods No. 1604, No. 1024 and No. 1501 of the National Institute of Occupational Safety and Health (NIOSH), respectively. The US Environmental Protection Agency (USEPA) method was used to assess carcinogenic and health risks. Results. The average occupational exposure to ABS was 560.82 µg m-3 for 1,3-butadiene, 122.8 µg m-3 for acrylonitrile and 1.92 µg m-3 for styrene. The average lifetime cancer risk in the present study was 2.71 × 10-3 for 1,3-butadiene, 2.1 × 10-3 for acrylonitrile and 6.6 × 10-3 for styrene. Also, the mean non-cancer risk (hazard quotient) among all participants for each of 1,3-butadiene, acrylonitrile and styrene was 4.04 ± 6.93, 10.82 ± 14.76 and 0.19 ± 0.11, respectively. Conclusion. The values of carcinogenic and health risks in the majority of the subjects were within the unacceptable risk levels due to exposure to ABS vapors. Hence, corrective actions are required to protect the workers from non-cancer and cancer risks.Objectives. This study aimed to assess carcinogenic and health risks of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene (ABS) in the petrochemical industry. Methods. This cross-sectional study was conducted in a petrochemical plant producing ABS copolymers. Respiratory exposure to each of acrylonitrile, 1,3-butadiene and styrene was measured using methods No. 1604, No. 1024 and No. 1501 of the National Institute of Occupational Safety and Health (NIOSH), respectively. The US Environmental Protection Agency (USEPA) method was used to assess carcinogenic and health risks. Results. The average occupational exposure to ABS was 560.82 µg m-3 for 1,3-butadiene, 122.8 µg m-3 for acrylonitrile and 1.92 µg m-3 for styrene. The average lifetime cancer risk in the present study was 2.71 × 10-3 for 1,3-butadiene, 2.1 × 10-3 for acrylonitrile and 6.6 × 10-3 for styrene. Also, the mean non-cancer risk (hazard quotient) among all participants for each of 1,3-butadiene, acrylonitrile and styrene was 4.04 ± 6.93, 10.82 ± 14.76 and 0.19 ± 0.11, respectively. Conclusion. The values of carcinogenic and health risks in the majority of the subjects were within the unacceptable risk levels due to exposure to ABS vapors. Hence, corrective actions are required to protect the workers from non-cancer and cancer risks.
Author Nikbakht, Neda
Soltanzadeh, Ahmad
Sadeghi-Yarandi, Mohsen
Sajedian, Ali Asghar
Seifi, Fatemeh
Koobasi, Rozhin
Ahmadi-Moshiran, Vahid
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SubjectTerms 1,3-butadiene
acrylonitrile
carcinogenic risk
hazard quotient
petrochemical industry
styrene
Title Carcinogenic and health risk assessment of respiratory exposure to acrylonitrile, 1,3-butadiene and styrene in the petrochemical industry using the US Environmental Protection Agency method
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