Epigenetic mechanisms activated by childhood adversity

• Published in: Epigenomics Vol. 12; no. 14; pp. 1239 - 1255
• Main Authors: Krause, Bernardo J, Artigas, Rocio, Sciolla, Andres F, Hamilton, James
• Format: Journal Article
• Language: English
• Published: England Future Medicine Ltd 01.07.2020
• Subjects: abuse; adversity; childhood trauma; chronic diseases; epigenetics; childhood trauma; abuse; adversity; chronic diseases; epigenetics

Adverse childhood experiences (ACE) impair health and life expectancy and may result in an epigenetic signature that drives increased morbidity primed during early stages of life. This literature review focuses on the current evidence for epigenetic-mediated programming of brain and immune function...