Effects of deflazacort versus prednisone on bone mass, body composition, and lipid profile : A randomized, double blind study in kidney transplant patients

• Published in: The journal of clinical endocrinology and metabolism Vol. 83; no. 11; pp. 3795 - 3802
• Main Authors: LIPPUNER, K, CASEZ, J.-P, HORBER, F. F, JAEGER, P
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Endocrine Society 01.11.1998
• Subjects: Biological and medical sciences; Body Composition - drug effects; Bone Density - drug effects; Carbohydrate Metabolism; Double-Blind Method; Female; Glucocorticoids - adverse effects; Humans; Immunomodulators; Immunosuppressive Agents - adverse effects; Kidney Transplantation - adverse effects; Lipid Metabolism; Lumbosacral Region; Male; Medical sciences; Middle Aged; Pharmacology. Drug treatments; Prednisone - adverse effects; Pregnenediones - adverse effects; Prospective Studies; Switzerland; Europe; Human; Corticosteroid; Deflazacort; Treatment efficiency; Prednisone; Transplantation; Density; Body composition; Kidney; Chemotherapy; Lipemia; Bone mass; Treatment; Mineral bone; Surgery; Double blind study; Adult; Immunosuppressive agent

To compare the effects of deflazacort (DEFLA) vs. prednisone (PRED) on bone mineral density (BMD), body composition, and lipids, 24 patients with end-stage renal disease were randomized in a double blind design and followed 78 weeks after kidney transplantation. BMD and body composition were assesse...