A meta-analysis of thromboembolic prophylaxis in total knee arthroplasty

• Published in: The Journal of arthroplasty Vol. 16; no. 3; pp. 293 - 300
• Main Authors: Brookenthal, K.R., Freedman, K.B., Lotke, P.A., Fitzgerald, R.H., Lonner, J.H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2001
• Subjects: Aged; Arthroplasty, Replacement, Knee; Aspirin - therapeutic use; Female; Heparin, Low-Molecular-Weight - therapeutic use; Humans; Male; meta-analysis; Postoperative Complications - prevention & control; Randomized Controlled Trials as Topic; thromboembolic disease; total knee arthroplasty; Venous Thrombosis - prevention & control; Warfarin - therapeutic use; meta-analysis; total knee arthroplasty; thromboembolic disease

Deep venous thrombosis (DVT) is common in total knee arthroplasty (TKA). Because of the rarity of the most serious outcomes, most randomized controlled trials lack the power to analyze these outcomes. A meta-analysis was performed for agents used in DVT prophylaxis in TKA employing a Medline literat...