Synthesis, characterization and cells and tissues imaging of carbon quantum dots
Compare to other quantum dots, carbon quantum dots have its own incomparable advantages, such as low cell toxicity, favorable biocompatibility, cheap production cost, mild reaction conditions, easy to large-scale synthesis and functionalization. In this thesis, we took citric acid monohydrate and di...
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| Published in | Optical materials Vol. 72; pp. 15 - 19 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
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Elsevier B.V
01.10.2017
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| Subjects | |
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| Abstract | Compare to other quantum dots, carbon quantum dots have its own incomparable advantages, such as low cell toxicity, favorable biocompatibility, cheap production cost, mild reaction conditions, easy to large-scale synthesis and functionalization. In this thesis, we took citric acid monohydrate and diethylene glycol bis (3-aMinopropyl) ether as materials, used decomposition method to acquire carbon quantum dots (CQDs) which can emission blue fluorescence under ultraviolet excitation. In the aspect of application, we achieved the biological imaging of CQDs in vivo and in vitro.
TEM image (HRTEM inset) of the CQDs prepared. [Display omitted]
•A novel carbon quantum dots (CQDs) has been successfully fabricated by hydrothermal method.•The CQDs proposed exhibits a uniform spherical shape and a narrow size distribution of 8.0 ± 3.0 nm in diameter.•A strong PL emission spectrum centered at 440 nm was observed when it was excited at 300 nm and the quantum yield is 11%.•The CQDs exhibits very low toxicity to NCI-H460 cells in vitro when the concentration is lower than 340.0 mM.•The CQDs have be applied to NCI-H460 cells imaging and tissue section imaging for kidney and liver. |
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| AbstractList | Compare to other quantum dots, carbon quantum dots have its own incomparable advantages, such as low cell toxicity, favorable biocompatibility, cheap production cost, mild reaction conditions, easy to large-scale synthesis and functionalization. In this thesis, we took citric acid monohydrate and diethylene glycol bis (3-aMinopropyl) ether as materials, used decomposition method to acquire carbon quantum dots (CQDs) which can emission blue fluorescence under ultraviolet excitation. In the aspect of application, we achieved the biological imaging of CQDs in vivo and in vitro.
TEM image (HRTEM inset) of the CQDs prepared. [Display omitted]
•A novel carbon quantum dots (CQDs) has been successfully fabricated by hydrothermal method.•The CQDs proposed exhibits a uniform spherical shape and a narrow size distribution of 8.0 ± 3.0 nm in diameter.•A strong PL emission spectrum centered at 440 nm was observed when it was excited at 300 nm and the quantum yield is 11%.•The CQDs exhibits very low toxicity to NCI-H460 cells in vitro when the concentration is lower than 340.0 mM.•The CQDs have be applied to NCI-H460 cells imaging and tissue section imaging for kidney and liver. |
| Author | Wang, Yiting Zhou, JingE Li, Qilong Wang, Jing Yu, Lei Zhu, Jianzhong Peng, Hui |
| Author_xml | – sequence: 1 givenname: Jing surname: Wang fullname: Wang, Jing – sequence: 2 givenname: Qilong surname: Li fullname: Li, Qilong – sequence: 3 givenname: JingE surname: Zhou fullname: Zhou, JingE – sequence: 4 givenname: Yiting surname: Wang fullname: Wang, Yiting email: ytwang@nbic.ecnu.edu.cn – sequence: 5 givenname: Lei surname: Yu fullname: Yu, Lei – sequence: 6 givenname: Hui surname: Peng fullname: Peng, Hui – sequence: 7 givenname: Jianzhong surname: Zhu fullname: Zhu, Jianzhong email: jzzhu714@163.com |
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| Title | Synthesis, characterization and cells and tissues imaging of carbon quantum dots |
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