Association between Adherence to a Mediterranean Diet Pattern and DNA Methylation of the Main Autophagy-Related Genes

• Published in: Current developments in nutrition Vol. 6; no. Supplement_1; p. 6
• Main Authors: Corella, Dolores, Coltell, Oscar, Fernández-Carrión, Rebeca, Portolés, Olga, Francés, Francesc, Saiz, Carmen, Barragán, Rocío, Castelló-Ponce, Ana, Guillem-Saiz, Patricia, Sorlí, Jose
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Inc 01.06.2022; Oxford University Press
• Subjects: Aging and Chronic Disease; Autophagy; DNA methylation; Genes; Proteins

Autophagy is a dynamic process responsible for protein degradation/recycling as a protective mechanism in response to stress and inflammation. Its deregulation has been associated with common cv and brain diseases. In animal models, autophagy activity is regulated by epigenetic mechanisms in respons...