The protective effect of breast feeding in relation to sudden infant death syndrome (SIDS): III. Detection of IgA antibodies in human milk that bind to bacterial toxins implicated in SIDS

• Published in: FEMS immunology and medical microbiology Vol. 25; no. 1-2; pp. 175 - 182
• Main Authors: Gordon, Ann E., Saadi, Abdulrahman T., MacKenzie, Doris A.C., Molony, Neil, James, Valerie S., Weir, Donald M., Busuttil, Anthony, Blackwell, C. Caroline
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.08.1999; Oxford University Press
• Subjects: Adult; Animals; Antibodies; Antibodies, Bacterial - analysis; Antibodies, Bacterial - immunology; Baby foods; Bacteria; Bacterial Toxins; Breast; Breast Feeding; Breast milk; Breastfeeding & lactation; Clostridium perfringens; Clostridium perfringens - immunology; Clostridium perfringens - metabolism; Enterotoxins - immunology; Enzyme-Linked Immunosorbent Assay; Epidemiology; Female; Humans; Immunoglobulin A; Immunoglobulin A - analysis; Immunoglobulin A - immunology; Immunoglobulins; Infant; Infant Food; Infant, Newborn; Infants; Milk; Milk, Human - immunology; Nose - microbiology; Pharynx - microbiology; Septic shock; SIDS; Standard deviation; Staphylococcal enterotoxin A; Staphylococcal enterotoxin C; Staphylococcal enterotoxin F; Staphylococcus aureus - immunology; Staphylococcus aureus - isolation & purification; Staphylococcus aureus - metabolism; Sudden Infant Death - prevention & control; Sudden infant death syndrome; Superantigens; Toxic shock syndrome; Toxins; Sudden infant death syndrome; Breast feeding; Immunoglobulin A

Abstract Two toxin-producing bacteria implicated in sudden infant death syndrome (SIDS) are Staphylococcus aureus and Clostridium perfringens. Epidemiological studies have shown that breast feeding reduces an infant's risk of SIDS. This protective effect could be due partly to IgA antibodies to...