Estimating metabolite networks subject to dietary preferences and lifestyle

• Published in: Metabolomics Vol. 21; no. 5; p. 105
• Main Authors: Bartzis, Georgios, Peeters, Carel F. W., Uh, Hae-Won, Houwing-Duistermaat, Jeanine J., van Eeuwijk, Fred A.
• Format: Journal Article
• Language: English
• Published: New York Springer US 11.08.2025; Springer Nature B.V
• Subjects: Adult; Age; Biochemistry; Biomedical and Life Sciences; Biomedicine; Cell Biology; Developmental Biology; Diet; Discriminant analysis; Epidemiology; Female; Food; Genetic diversity; Genetics; Humans; Life Sciences; Life Style; Lifestyles; Male; Metabolic Networks and Pathways; Metabolic syndrome; Metabolites; Metabolome; Metabolomics; Metabolomics - methods; Middle Aged; Molecular Medicine; Nutrition research; Original; Original Article; Phenotypes; Phenotypic variations; Polymorphism, Single Nucleotide; Questionnaires; Single-nucleotide polymorphism; Metabolites; Network reconstruction; Repeated measures

Introduction The metabolome is an intermediate between DNA variation and clinical phenotypes. Metabolomics have been widely used in biomedical studies for reflecting physiological changes in response to variation coming from various sources, such as diet, environment, time, and lifestyle. While life...