Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire - Emerson, Ryan O; DeWitt, William S; Vignali, Marissa; Gravley, Jenna; Hu, Joyce K; Osborne, Edward J; Desmarais, Cindy; Klinger, Mark; Carlson, Christopher S; Hansen, John A; Rieder, Mark; Robins, Harlan S (Nature genetics, 2017)
Keywords: 45; 45/23; 631/114; 631/208/248; 631/208/514/1948; 631/250; Agriculture; Algorithms; Animal Genetics and Genomics; Antigens; Biomedicine; Cancer Research; Coding; Cohort Studies; Cytomegalovirus; Cytomegalovirus - genetics; Cytomegalovirus - immunology; Cytomegalovirus - physiology; Cytotoxicity; Diagnostic systems; Epitopes, T-Lymphocyte - genetics; Epitopes, T-Lymphocyte - immunology; Exposure; Gene Function; High-Throughput Nucleotide Sequencing - methods; Histocompatibility Testing - methods; HLA Antigens - genetics; HLA Antigens - immunology; HLA-A Antigens - genetics; HLA-A Antigens - immunology; HLA-B Antigens - genetics; HLA-B Antigens - immunology; Host-Pathogen Interactions - immunology; Human Genetics; Humans; Immunology; In vitro methods and tests; Infections; Lymphocytes; Lymphocytes T; Medical research; Models, Immunological; Pathogens; Receptors; Receptors, Antigen, T-Cell - genetics; Receptors, Antigen, T-Cell - immunology; Reproducibility of Results; Signatures; T cell receptors; T-Lymphocytes - immunology; T-Lymphocytes - metabolism; T-Lymphocytes - virology; Viral infections