Brain cortical amino acids measured by intracerebral dialysis in portacaval shunted rats

• Published in: Neurochemical research Vol. 12; no. 3; p. 265
• Main Authors: Tossman, U, Delin, A, Eriksson, L S, Ungerstedt, U
• Format: Journal Article
• Language: English
• Published: United States 01.03.1987
• Subjects: Amino Acids - analysis; Animals; Brain - physiopathology; Extracellular Space - analysis; Hepatic Encephalopathy - metabolism; Hepatic Encephalopathy - physiopathology; Male; Motor Activity - physiology; Parietal Lobe - analysis; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Synaptic Transmission

The extracellular amino acid content was measured in the parietal cortex in portacaval and sham operated rats, using the brain dialysis technique. The amino acid content of the perfusate was determined for 10 min before and during stimulation with potassium chloride. Basal levels of aspartate, gluta...