Colon-targeted delivery of tacrolimus using pH-responsive polymeric nanoparticles for murine colitis therapy
[Display omitted] The present study aimed at constructing an oral nanoparticle delivery system loaded with tacrolimus (FK506) for effective treatment of inflammatory bowel disease. A FK506/HP-β-CD inclusion compound was prepared by grinding to increase drug solubility. To address the side- effects i...
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Published in | International journal of pharmaceutics Vol. 606; p. 120836 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Elsevier B.V
05.09.2021
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Subjects | |
Online Access | Get full text |
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