Meta-Analysis of Odds Ratios: Current Good Practices

• Published in: Medical care Vol. 55; no. 4; p. 328
• Main Authors: Chang, Bei-Hung, Hoaglin, David C
• Format: Journal Article
• Language: English
• Published: United States 01.04.2017
• Subjects: Endoscopy; Esophageal and Gastric Varices - therapy; Humans; Liver Cirrhosis - therapy; Meta-Analysis as Topic; Odds Ratio; Randomized Controlled Trials as Topic; Research Design; Sclerotherapy; Software

Many systematic reviews of randomized clinical trials lead to meta-analyses of odds ratios (ORs). The customary methods of estimating an overall OR involve weighted averages of the individual trials' estimates of the logarithm of the OR. That approach, however, has several shortcomings, arising...