Expectations of preventative benefits and risk behaviors in a randomized trial evaluating oral HIV preexposure prophylaxis candidates

• Published in: AIDS care Vol. 36; no. 8; p. 1172
• Main Authors: Sugarman, Jeremy, Weir, Brian W, Dun, Chen, Gulick, Roy M, Wilkin, Timothy J, Mayer, Kenneth H, McCauley, Marybeth, Weinfurt, Kevin P
• Format: Journal Article
• Language: English
• Published: England 02.08.2024
• Subjects: Administration, Oral; Adult; Anti-HIV Agents - administration & dosage; Anti-HIV Agents - therapeutic use; Female; Health Knowledge, Attitudes, Practice; HIV Infections - prevention & control; Homosexuality, Male - psychology; Humans; Male; Middle Aged; Pre-Exposure Prophylaxis - methods; Risk-Taking; Sexual Behavior; preventive misconception; HIV prevention; ethics; behaviors; SDG 3: Good health and well-being

When participants enrolled in an HIV prevention trial hold a preventive misconception (PM) - expectations that experimental interventions will confer protection from HIV infection - they may engage in behaviors that increase their risk of acquiring HIV. This can raise ethical concerns about whether...