Molybdenum-induced changes in the epiphyseal growth plate

• Published in: Calcified tissue international Vol. 53; no. 3; p. 180
• Main Authors: Parry, N M, Phillippo, M, Reid, M D, McGaw, B A, Flint, D J, Loveridge, N
• Format: Journal Article
• Language: English
• Published: United States 01.09.1993
• Subjects: Alkaline Phosphatase - blood; Animals; Calcifediol - blood; Calcitriol - blood; Calcium - blood; Cell Division - drug effects; Copper - blood; Copper - deficiency; Diet; Glucosephosphate Dehydrogenase - blood; Growth Plate - cytology; Growth Plate - drug effects; Insulin-Like Growth Factor I - metabolism; Liver - metabolism; Male; Molybdenum - administration & dosage; Molybdenum - pharmacology; Phosphorus - blood; Radioimmunoassay; Rats; Trace Elements - metabolism

Molybdenum (Mo), at high concentrations, induces changes in the epiphyseal growth plate through its effects on copper (Cu) metabolism but it is unclear whether or not Mo can induce changes independent of its effects on copper status. To this end, the effect of Mo on longitudinal bone growth was exam...