Black Hole Quenchers for SERRS Imaging of CXCR4 Expression at Single‐Cell Level During Treatment

• Published in: Advanced functional materials Vol. 35; no. 11
• Main Authors: Zhu, Congzheng, Li, Jin, Chen, Xinru, Fu, Longwen, Zhang, Zhiyang, Wang, Yunqing, Wang, Xiaoyan, Chen, Lingxin
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc 01.03.2025
• Subjects: Biomarkers; black hole quenchers; Chemokine receptors; Conjugation; CXCR4; Fluorescence; Imaging; Internal conversion; Raman reporters; Raman spectra; Reagents; Resonance; Resonance scattering; SERRS; triple‐negative breast cancer cells

CXC chemokine receptor 4 (CXCR4) is recently regarded as a valuable biomarker for triple‐negative breast cancer (TNBC) metastasis but lacks available imaging reagents. Surface‐enhanced resonance Raman scattering (SERRS) with resonant dyes has emerged as a powerful tool for single‐cell imaging becaus...