Long-Lasting Increased Risk of Human Papillomavirus–Related Carcinomas and Premalignancies After Cervical Intraepithelial Neoplasia Grade 3: A Population-Based Cohort Study

• Published in: Journal of clinical oncology Vol. 35; no. 22; pp. 2542 - 2550
• Main Authors: Ebisch, Renée M.F., Rutten, Dominiek W.E., IntHout, Joanna, Melchers, Willem J.G., Massuger, Leon F.A.G., Bulten, Johan, Bekkers, Ruud L.M., Siebers, Albert G.
• Format: Journal Article
• Language: English
• Published: United States 01.08.2017
• Subjects: Adult; Aged; Aged, 80 and over; Anus Neoplasms - epidemiology; Anus Neoplasms - virology; Case-Control Studies; Cervical Intraepithelial Neoplasia - diagnosis; Cervical Intraepithelial Neoplasia - pathology; Female; Follow-Up Studies; Genital Neoplasms, Female - epidemiology; Genital Neoplasms, Female - virology; Humans; Middle Aged; Neoplasm Grading; Neoplasms, Second Primary - epidemiology; Neoplasms, Second Primary - virology; Netherlands - epidemiology; Oropharyngeal Neoplasms - epidemiology; Oropharyngeal Neoplasms - virology; Papillomavirus Infections - complications; Precancerous Conditions - epidemiology; Precancerous Conditions - virology; Registries; Retrospective Studies; Risk Assessment; Young Adult

Purpose The aim of this study was to determine the risk of human papillomavirus (HPV)-related carcinomas and premalignancies in women diagnosed with cervical intraepithelial neoplasia grade 3 (CIN3). Knowledge of this risk is important to preventing the development and progression of other HPV-relat...