The effect of sacubitril/valsartan compared to olmesartan on cardiovascular remodelling in subjects with essential hypertension: the results of a randomized, double-blind, active-controlled study - Schmieder, Roland E; Wagner, Frank; Mayr, Michael; Delles, Christian; Ott, Christian; Keicher, Christian; Hrabak-Paar, Maja; Heye, Tobias; Aichner, Solveig; Khder, Yasser; Yates, Denise; Albrecht, Diego; et al. (European heart journal, 2017)
Keywords: Aminobutyrates - therapeutic use; Angiotensin Receptor Antagonists - therapeutic use; Antihypertensive Agents - therapeutic use; Aorta - drug effects; Aorta, Thoracic - drug effects; Biphenyl Compounds; Blood Pressure - drug effects; Double-Blind Method; Drug Combinations; Essential Hypertension - drug therapy; Essential Hypertension - physiopathology; Female; Heart Failure - physiopathology; Heart Failure - prevention & control; Humans; Hypertrophy, Left Ventricular - physiopathology; Hypertrophy, Left Ventricular - prevention & control; Imidazoles - therapeutic use; Magnetic Resonance Angiography; Male; Medication Adherence; Middle Aged; Neprilysin; Tetrazoles - therapeutic use; Valsartan; Vascular Stiffness - drug effects; Ventricular Remodeling - drug effects; Heart failure; Hypertension; Neprilysin; Arterial stiffness; Angiotensin; Left ventricular hypertrophy