CYP2C93 and 13 alleles significantly affect the pharmacokinetics of irbesartan in healthy Korean subjects - Choi, Chang-Ik; Kim, Mi-Jeong; Chung, Eun-Kyung; Lee, Hye-In; Jang, Choon-Gon; Bae, Jung-Woo; Lee, Seok-Yong (European journal of clinical pharmacology, 2012)
Keywords: Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Genetics; Health; Kinetics; Medical sciences; Pharmacogenetics; Pharmacology; Pharmacology. Drug treatments; Pharmacology/Toxicology; Asia; Korea; CYP2C9; Irbesartan; Pharmacokinetics; Genetic polymorphism; Imidazole derivatives; Tetrazole derivatives; Genetic variability; Isozyme; Peptide hormone; Octapeptide; Genetics; Angiotensin II; Human; Healthy subject; Enzyme; Cytochrome P450; Genotype; Genetic polymorphisms; Renin angiotensin system; Allele; Biphenyl derivatives; Antihypertensive agent; Sartan derivatives; Angiotensin antagonist; CYP2C9 gene; Polymorphism