Diagnosis and management of Wegener's granulomatosis in a dog

A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagno...

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Published inJournal of veterinary dentistry Vol. 23; no. 4; p. 231
Main Authors Krug, William, Marretta, Sandra Manfra, de Lorimier, Louis-Philippe, White, Dean K, Borst, Luke
Format Journal Article
LanguageEnglish
Published United States 01.12.2006
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Abstract A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagnostic investigations for infectious, neoplastic, or other inflammatory conditions all provided negative results. Management with a combination of immunosuppressive agents resulted in complete resolution and remission of the presenting lesions and associated clinical signs.
AbstractList A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagnostic investigations for infectious, neoplastic, or other inflammatory conditions all provided negative results. Management with a combination of immunosuppressive agents resulted in complete resolution and remission of the presenting lesions and associated clinical signs.
Author Marretta, Sandra Manfra
Borst, Luke
White, Dean K
Krug, William
de Lorimier, Louis-Philippe
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Snippet A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional...
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StartPage 231
SubjectTerms Animals
Diagnosis, Differential
Dog Diseases - diagnosis
Dog Diseases - drug therapy
Dogs
Gingivitis - diagnosis
Gingivitis - drug therapy
Gingivitis - veterinary
Granulomatosis with Polyangiitis - diagnosis
Granulomatosis with Polyangiitis - drug therapy
Granulomatosis with Polyangiitis - veterinary
Immunohistochemistry - veterinary
Immunosuppressive Agents - therapeutic use
Male
Treatment Outcome
Title Diagnosis and management of Wegener's granulomatosis in a dog
URI https://www.ncbi.nlm.nih.gov/pubmed/17286129
Volume 23
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