Diagnosis and management of Wegener's granulomatosis in a dog
A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagno...
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Published in | Journal of veterinary dentistry Vol. 23; no. 4; p. 231 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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United States
01.12.2006
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Abstract | A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagnostic investigations for infectious, neoplastic, or other inflammatory conditions all provided negative results. Management with a combination of immunosuppressive agents resulted in complete resolution and remission of the presenting lesions and associated clinical signs. |
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AbstractList | A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional biopsies supported a diagnosis of Wegener's granulomatosis, an autoimmune vasculitis previously unreported in the veterinary literature. Diagnostic investigations for infectious, neoplastic, or other inflammatory conditions all provided negative results. Management with a combination of immunosuppressive agents resulted in complete resolution and remission of the presenting lesions and associated clinical signs. |
Author | Marretta, Sandra Manfra Borst, Luke White, Dean K Krug, William de Lorimier, Louis-Philippe |
Author_xml | – sequence: 1 givenname: William surname: Krug fullname: Krug, William email: wvkrug@ncsu.edu organization: Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, 61802, USA. wvkrug@ncsu.edu – sequence: 2 givenname: Sandra Manfra surname: Marretta fullname: Marretta, Sandra Manfra – sequence: 3 givenname: Louis-Philippe surname: de Lorimier fullname: de Lorimier, Louis-Philippe – sequence: 4 givenname: Dean K surname: White fullname: White, Dean K – sequence: 5 givenname: Luke surname: Borst fullname: Borst, Luke |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/17286129$$D View this record in MEDLINE/PubMed |
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Snippet | A four-year-old maele/neutered mixed-breed dog was prsented for severe, multifocal, proliferative gingivitis. Histopathologic examination of incisional... |
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SubjectTerms | Animals Diagnosis, Differential Dog Diseases - diagnosis Dog Diseases - drug therapy Dogs Gingivitis - diagnosis Gingivitis - drug therapy Gingivitis - veterinary Granulomatosis with Polyangiitis - diagnosis Granulomatosis with Polyangiitis - drug therapy Granulomatosis with Polyangiitis - veterinary Immunohistochemistry - veterinary Immunosuppressive Agents - therapeutic use Male Treatment Outcome |
Title | Diagnosis and management of Wegener's granulomatosis in a dog |
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