Heart rate variability after BRL37344, a beta-3 agonist, in experimental bladder outlet obstruction

• Published in: Postȩpy higieny i medycyny doświadczalnej Vol. 67; pp. 848 - 858
• Main Authors: Dobrek, Łukasz, Baranowska, Agnieszka, Thor, Piotr J
• Format: Journal Article
• Language: English
• Published: Poland 12.08.2013
• Subjects: Adrenergic beta-Agonists - pharmacology; Animals; Autonomic Nervous System - drug effects; Disease Models, Animal; Ethanolamines - pharmacology; Female; Heart Rate - drug effects; Male; Organ Size; Prostatic Hyperplasia - complications; Prostatic Hyperplasia - physiopathology; Rats; Rats, Wistar; Urinary Bladder - pathology; Urinary Bladder Neck Obstruction - drug therapy; Urinary Bladder Neck Obstruction - etiology; Urinary Bladder Neck Obstruction - physiopathology; Urinary Bladder, Overactive - etiology; Urinary Bladder, Overactive - physiopathology

Bladder overactivity symptoms accompany benign prostatic hyperplasia (BPH) syndrome. The autonomic nervous system (ANS) disturbances may be involved in bladder dysfunction. An ameliorating effect on bladder overactivity is being assigned to the currently investigated β-3 adrenoreceptor agonists. How...