Gender flip-flop association between genetic variations of NEDD4L and metabolic syndrome in the Kazakh general population

• Published in: Genetics and molecular research Vol. 13; no. 1; pp. 22 - 31
• Main Authors: Wang, H.M., Li, N.F., Hong, J., Zhou, L., Chang, J.H.
• Format: Journal Article
• Language: English
• Published: Brazil 08.01.2014
• Subjects: Adult; Case-Control Studies; China; Endosomal Sorting Complexes Required for Transport - genetics; Exons; Female; Humans; Male; Metabolic Syndrome - genetics; Middle Aged; Nedd4 Ubiquitin Protein Ligases; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Sex Factors; Ubiquitin-Protein Ligases - genetics

Genetic variation is thought to contribute to etiology of metabolic syndrome (MS). Neural precursor cell expressed developmentally downregulated 4-like gene (NEDD4L) is a candidate gene for MS. This study investigated the relationship between variations of NEDD4L and MS in the Kazakh, which is an id...