The effects of quetiapine on sleep in recovering alcohol-dependent subjects: a pilot study

• Published in: Journal of clinical psychopharmacology Vol. 34; no. 3; p. 350
• Main Authors: Chakravorty, Subhajit, Hanlon, Alexandra L, Kuna, Samuel T, Ross, Richard J, Kampman, Kyle M, Witte, Lauren M, Perlis, Michael L, Oslin, David W
• Format: Journal Article
• Language: English
• Published: United States 01.06.2014
• Subjects: Alcoholism - rehabilitation; Antipsychotic Agents - administration & dosage; Antipsychotic Agents - therapeutic use; Craving; Delayed-Action Preparations; Dibenzothiazepines - administration & dosage; Dibenzothiazepines - therapeutic use; Double-Blind Method; Follow-Up Studies; Humans; Male; Middle Aged; Pilot Projects; Polysomnography; Prospective Studies; Psychomotor Performance - drug effects; Quetiapine Fumarate; Severity of Illness Index; Sleep Initiation and Maintenance Disorders - drug therapy; Sleep Initiation and Maintenance Disorders - etiology; Surveys and Questionnaires; Treatment Outcome

The aim of this hypothesis-generating pilot study was to assess prospectively the objective and subjective effects of treatment with quetiapine XR on sleep during early recovery from alcohol dependence (AD). Recovering subjects with AD and sleep disturbance complaints were treated with quetiapine XR...