Clinical evaluation of pazopanib eye drops in healthy subjects and in subjects with neovascular age-related macular degeneration - Singh, Rishi; Wurzelmann, John I; Ye, Li; Henderson, Linda; Hossain, Mohammad; Trivedi, Trupti; Kelly, Deborah S (Retina (Philadelphia, Pa.), 2014)
Keywords: Administration, Topical; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors - adverse effects; Angiogenesis Inhibitors - pharmacokinetics; Biological Availability; Double-Blind Method; Female; Healthy Volunteers; Humans; Male; Middle Aged; Ophthalmic Solutions; Protein-Tyrosine Kinases - antagonists & inhibitors; Pyrimidines - adverse effects; Pyrimidines - pharmacokinetics; Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors; Retina - drug effects; Sulfonamides - adverse effects; Sulfonamides - pharmacokinetics; Tissue Distribution; Visual Acuity - drug effects; Wet Macular Degeneration - drug therapy; Wet Macular Degeneration - metabolism; Young Adult