Detection and biochemical characterization of circulating proteasomes in dog plasma

• Published in: Research in veterinary science Vol. 162; p. 104950
• Main Authors: Cerruti, F., Borrelli, A., Degiovanni, A., Mengozzi, G., Borella, F., Cascio, P.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.09.2023
• Subjects: blood; Canine plasma; Circulating 20S; dogs; Extracellular proteasome; family; milk; peptides; pericardium; Proteasomal activities; Proteasome activators; proteasome endopeptidase complex; proteinases; saliva; sweat; urine; veterinary medicine; Circulating 20S; Proteasomal activities; Canine plasma; Proteasome activators; Extracellular proteasome

A growing body of evidence convincingly indicates that proteasomes are not located exclusively within cells but also in different extracellular compartments. In humans, in fact, this large multimeric protease has been identified in many body fluids and secretions such as blood, urine, tears, sweat,...