Differentiating Structurally Similar Fentanyl Analogs by Comparing Density Functional Theory (DFT) Calculations and Surface-Enhanced Raman Spectroscopy (SERS) Results

• Published in: Applied spectroscopy p. 37028241246010
• Main Authors: Dogruer Erkok, Sevde, Hernandez, Emily, Cruz, Jordi, Mebel, Alexander M, McCord, Bruce
• Format: Journal Article
• Language: English
• Published: United States 01.07.2024
• Subjects: DFT; SERS; density functional theory; Fentanyl; fentanyl analogs; portable Raman; surface-enhanced Raman spectroscopy

Fentanyl and fentanyl analogs are the main cause of recent overdose deaths in the United States. The presence of fentanyl analogs in illicit drugs makes it difficult to estimate their potencies. This makes the detection and differentiation of fentanyl analogs critically significant. Surface-enhanced...