Omega-3 deficiency and neurodegeneration in the substantia nigra: Involvement of increased nitric oxide production and reduced BDNF expression - Cardoso, Henriqueta Dias; Santos Junior, Eraldo Fonseca dos; de Santana, David Filipe; Gonçalves-Pimentel, Catarina; Angelim, Monara Kaélle; Isaac, Alinny R.; Lagranha, Cláudia Jacques; Guedes, Rubem Carlos Araújo; Beltrão, Eduardo Isidoro; Morya, Edgar; Rodrigues, Marcelo Cairrão Araújo; Andrade-da-Costa, Belmira Lara da Silveira (Biochimica et biophysica acta, 2014)
Keywords: adulthood; Animals; antioxidants; brain; Brain-Derived Neurotrophic Factor - analysis; Brain-Derived Neurotrophic Factor - physiology; catalase; Catalase - metabolism; diet; dietary restriction; enzyme activity; essential fatty acids; Fatty Acids, Omega-3 - physiology; Female; homeostasis; Lipid Peroxidation; Male; neurons; nitric oxide; Nitric Oxide - biosynthesis; Oxidative Stress; Parkinson disease; Parkinson Disease - etiology; pregnancy; Rats; Rats, Wistar; risk; Substantia Nigra - physiology; superoxide dismutase; Superoxide Dismutase - metabolism; tyrosine 3-monooxygenase; Tyrosine 3-Monooxygenase - analysis; young adults; Oxidative stress; Striatum; Brain-derived neurotrophic factor; Dopamine; Docosahexaenoic acid; Lipoperoxidation