Pre-operative serum levels of sialyl Tn antigen predict liver metastasis and poor prognosis in patients with gastric cancer

• Published in: European journal of surgical oncology Vol. 27; no. 8; pp. 731 - 739
• Main Authors: Nakagoe, T, Sawai, T, Tsuji, T, Jibiki, M, Nanashima, A, Yamaguchi, H, Yasutake, T, Ayabe, H, Arisawa, K, Ishikawa, H
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.12.2001
• Subjects: Aged; Antigens, Tumor-Associated, Carbohydrate - analysis; Biomarkers, Tumor - analysis; CA19-9; Female; gastric cancer; Humans; liver metastasis; Liver Neoplasms - secondary; Male; Middle Aged; Predictive Value of Tests; Prognosis; prognostic factor; Prospective Studies; Reference Values; sialyl Lewisa; sialyl Tn; STN; Stomach Neoplasms - pathology; Stomach Neoplasms - surgery; Survival Analysis; liver metastasis; gastric cancer; prognostic factor; sialyl Lewisa; STN; CA19-9; sialyl Tn

Aims: To clarify the prognostic value of preoperative serum levels of sialyl Tn antigen (STN) for survival of gastric cancer patients. Methods: Pre-operative serum levels of STN, sialyl Lewisaantigen (CA19-9) and carcinoembryonic antigen (CEA) were examined in 180 patients who underwent resection of...