The Relationship Between Phosphodiesterase-5 Inhibitors and Nonarteritic Anterior Ischemic Optic Neuropathy

• Published in: Journal of neuro-ophthalmology Vol. 36; no. 2; pp. 193 - 196
• Main Author: Pomeranz, Howard D.
• Format: Journal Article
• Language: English
• Published: United States 01.06.2016
• Subjects: Erectile Dysfunction - drug therapy; Humans; Male; Optic Neuropathy, Ischemic - chemically induced; Phosphodiesterase 5 Inhibitors - adverse effects; Phosphodiesterase 5 Inhibitors - therapeutic use

A cause and effect relationship between phosphodiesterase-5 inhibitor (PDE5I) use and nonarteritic anterior ischemic optic neuropathy (NAION) has been hypothesized based on case reports. Review of literature. Thirty-nine case reports in the peer-reviewed medical literature have documented a possible...